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Fourth Type of Muscle Fiber Increases Endurance

January 3rd 2007 04:14
Muscles are made up of four types of fibers: two slow-twitch, one fast-twitch, and that other one. The fourth type, called IIX (read "two-ex"), is distributed throughout different muscles, making it difficult to study exactly when and for what purpose it is recruited. Using genetic manipulation in mice, Arany, et al., changed 15% IIX muscles into 100% IIX muscles. The mice lasted 25% longer on their exercise wheels than control mice.

Source: Cell Metabolism, Vol 5, Jan 2007


"The Transcriptional Coactivator PGC-1(beta) Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle" by Zoltan Arany, Nathan Lebrasseur, Carl Morris, Eric Smith, Wenli Yang, Yanhong Ma, Sherry Chin, and Bruce M. Spiegelman
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5 Comments. [ Add A Comment ]

Comment by katyzzz

January 4th 2007 00:43
Adele,

Really good information, wonder where it is all heading. Maybe towards me, very cryptic, explanation not possible.

I'm playing catch up, please be a little patient with me.

katyzzz

Comment by Adele

January 4th 2007 06:46
katyzzz,

Looking to become a genetically enhanced super-athlete? That's not for me. I'm happy with my moderate abilities.

Comment by Deorre

January 4th 2007 13:27
Damn--it opens up all sorts of possibilities, some kind of frightening.

Comment by Adele

January 4th 2007 14:54
Deorre,

It strikes me as something out of science fiction. I love those "what if" stories, but I don't want them to come true, either.

Comment by Lilla

January 6th 2007 02:41
Hi Adele,

... I suppose it's good to know, just incase one day you need to know... you know?

...

very interesting post this...
Thanks
)
Lilla

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