Fourth Type of Muscle Fiber Increases Endurance
January 3rd 2007 04:14
Muscles are made up of four types of fibers: two slow-twitch, one fast-twitch, and that other one. The fourth type, called IIX (read "two-ex"), is distributed throughout different muscles, making it difficult to study exactly when and for what purpose it is recruited. Using genetic manipulation in mice, Arany, et al., changed 15% IIX muscles into 100% IIX muscles. The mice lasted 25% longer on their exercise wheels than control mice.
Source: Cell Metabolism, Vol 5, Jan 2007
"The Transcriptional Coactivator PGC-1(beta) Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle" by Zoltan Arany, Nathan Lebrasseur, Carl Morris, Eric Smith, Wenli Yang, Yanhong Ma, Sherry Chin, and Bruce M. Spiegelman
Source: Cell Metabolism, Vol 5, Jan 2007
"The Transcriptional Coactivator PGC-1(beta) Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle" by Zoltan Arany, Nathan Lebrasseur, Carl Morris, Eric Smith, Wenli Yang, Yanhong Ma, Sherry Chin, and Bruce M. Spiegelman
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Comment by katyzzz
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Really good information, wonder where it is all heading. Maybe towards me, very cryptic, explanation not possible.
I'm playing catch up, please be a little patient with me.
katyzzz
Comment by Adele
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Looking to become a genetically enhanced super-athlete? That's not for me. I'm happy with my moderate abilities.
Comment by Deorre
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Comment by Adele
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It strikes me as something out of science fiction. I love those "what if" stories, but I don't want them to come true, either.
Comment by Lilla
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... I suppose it's good to know, just incase one day you need to know... you know?
...
very interesting post this...
Thanks
Lilla