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People Are Different From Mice

November 28th 2006 17:56
In the online article, "Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity", Minegishi, et al, discuss their findings relating to Tyk2 in a patient diagnosed with hyper-IgE syndrome (HIES). The findings differ from those expected from a mouse model. Mice immune systems without the Tyk2 can be stimulated using a certain procedure, where the human immune systems must have the Tyk2 already present.

Published in Immunity.



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Comment by katyzzz

November 29th 2006 11:41


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Adele,

Yes, this overreliance on animal studies is standing in the way of much research and the processing of thought to find solutions.

katyzzz


Comment by Adele

November 29th 2006 14:51


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I agree, katyzzz. Thanks for stopping by.

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