new-science
New Strategy for Elimination of Polio in India
November 22nd 2006 02:15
A paper in Science magazine indicates that a shift in strategy will eliminate polio in India. Nicholas Grassly, et al, state that switching from trivalent vaccines to monovalent vaccines will more effectively fight polio.
Trivalent vaccines contain three strains of polio in order to provide broader coverage, but the vaccine needs time in the recipient's digestive tract to work. Children with diarrhea, for instance, will not receive immunity from the vaccine. Monovalent vaccines contain only one strain of polio, which in this case is not bad, since one strain is much more prevalent in India. Monovalent vaccines work faster, so diarrhea should not interfere with their effectiveness.
Nature magazine has a summary of the paper. In it, several scientists express hope that polio will be eliminated in the world by the end of the decade.
Wikipedia on Polio.
Trivalent vaccines contain three strains of polio in order to provide broader coverage, but the vaccine needs time in the recipient's digestive tract to work. Children with diarrhea, for instance, will not receive immunity from the vaccine. Monovalent vaccines contain only one strain of polio, which in this case is not bad, since one strain is much more prevalent in India. Monovalent vaccines work faster, so diarrhea should not interfere with their effectiveness.
Nature magazine has a summary of the paper. In it, several scientists express hope that polio will be eliminated in the world by the end of the decade.
Wikipedia on Polio.
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